Hidetsugu Asada : rechercher sur Z-Library

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Articles (35)
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Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog

Asada, Hidetsugu, Horita, Shoichiro, Hirata, Kunio, Shiroishi, Mitsunori, Shiimura, Yuki, Iwanari, Hiroko, Hamakubo, Takao, Shimamura, Tatsuro, Nomura, Norimichi, Kusano-Arai, Osamu, Uemura, Tomoko, S

Journal:

Nature Structural and Molecular Biology

Année:

2018

Langue:

english

Fichier:

PDF, 2.10 MB

english, 2018

Sequence-specific gene silencing in murine muscle induced by electroporation-mediated transfer of short interfering RNA

Tsunao Kishida, Hidetsugu Asada, Satoshi Gojo, Suzuyo Ohashi, Masaharu Shin-Ya, Kakei Yasutomi, Ryu Terauchi, Kenji A. Takahashi, Toshikazu Kubo, Jiro Imanishi, Osam Mazda

Journal:

The Journal of Gene Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 156 KB

english, 2004

Interleukin-21 triggers both cellular and humoral immune responses leading to therapeutic antitumor effects against head and neck squamous cell carcinoma

Hiroshi Nakano, Tsunao Kishida, Hidetsugu Asada, Masaharu Shin-Ya, Takashi Shinomiya, Jiro Imanishi, Taketoshi Shimada, Shigeru Nakai, Minoru Takeuchi, Yasuo Hisa, Osam Mazda

Journal:

The Journal of Gene Medicine

Année:

2006

Langue:

english

Fichier:

PDF, 217 KB

english, 2006

Evaluation of thePichia pastorisexpression system for the production of GPCRs for structural analysis

Hidetsugu Asada, Tomoko Uemura, Takami Yurugi-Kobayashi, Mitsunori Shiroishi, Tatsuro Shimamura, Hirokazu Tsujimoto, Keisuke Ito, Taishi Sugawara, Takanori Nakane, Norimichi Nomura, Takeshi Murata, Ta

Journal:

Microbial Cell Factories

Année:

2011

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2011

Osteoblasts derived from osteophytes produce interleukin-6, interleukin-8, and matrix metalloproteinase-13 in osteoarthritis

Kei Sakao, Kenji A. Takahashi, Yuji Arai, Masazumi Saito, Kuniaki Honjo, Nobuyuki Hiraoka, Hidetsugu Asada, Masaharu Shin-Ya, Jiro Imanishi, Osam Mazda, Toshikazu Kubo

Journal:

Journal of Bone and Mineral Metabolism

Année:

2009

Langue:

english

Fichier:

PDF, 470 KB

english, 2009

Cysteine-to-serine shuffling using aSaccharomyces cerevisiaeexpression system improves protein secretion: case of a nonglycosylated mutant of miraculin, a taste-modifying protein

Keisuke Ito, Taishi Sugawara, Ayako Koizumi, Ken-ichiro Nakajima, Akiko Shimizu-Ibuka, Mitsunori Shiroishi, Hidetsugu Asada, Takami Yurugi-Kobayashi, Tatsuro Shimamura, Tomiko Asakura, Takumi Misaka,

Journal:

Biotechnology Letters

Année:

2011

Langue:

english

Fichier:

PDF, 312 KB

english, 2011

Electron spin resonance study of N-alkyl-N-(alkylthio)aminyl radicals

Miura, Yozo, Asada, Hidetsugu, Kinoshita, Masayoshi, Ohta, Katsuhisa

Journal:

Journal of Physical Chemistry

Année:

1983

Langue:

english

Fichier:

PDF, 803 KB

english, 1983

Bulky high-mannose-type N-glycan blocks the taste-modifying activity of miraculin

Keisuke Ito, Taishi Sugawara, Ayako Koizumi, Ken-ichiro Nakajima, Akiko Shimizu-Ibuka, Mitsunori Shiroishi, Hidetsugu Asada, Takami Yurugi-Kobayashi, Tatsuro Shimamura, Tomiko Asakura, Katsuyoshi Masu

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Année:

2010

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2010

Intravascular insulin gene delivery as potential therapeutic intervention in diabetes mellitus

Kakei Yasutomi, Yoshiki Itokawa, Hidetsugu Asada, Tsunao Kishida, Feng-De Cui, Suzuyo Ohashi, Satoshi Gojo, Yuji Ueda, Toshikazu Kubo, Hisakazu Yamagishi, Jiro Imanishi, Toshiyuki Takeuchi, Osam Mazda

Journal:

Biochemical and Biophysical Research Communications

Année:

2003

Langue:

english

Fichier:

PDF, 216 KB

english, 2003

Interleukin-12 genetic administration suppressed metastatic liver tumor unsusceptible to CTL

Yoshiki Itokawa, Osam Mazda, Yuji Ueda, Tsunao Kishida, Hidetsugu Asada, Feng-De Cui, Nobuaki Fuji, Hitoshi Fujiwara, Masaharu Shin-Ya, Kakei Yasutomi, Jiro Imanishi, Hisakazu Yamagishi

Journal:

Biochemical and Biophysical Research Communications

Année:

2004

Langue:

english

Fichier:

PDF, 177 KB

english, 2004

Intracellular interferon triggers Jak/Stat signaling cascade and induces p53-dependent antiviral protection

Masaharu Shin-Ya, Hideyo Hirai, Etsuko Satoh, Tsunao Kishida, Hidetsugu Asada, Fumiko Aoki, Masako Tsukamoto, Jiro Imanishi, Osam Mazda

Journal:

Biochemical and Biophysical Research Communications

Année:

2005

Langue:

english

Fichier:

PDF, 637 KB

english, 2005

Sonoporation using microbubble BR14 promotes pDNA/siRNA transduction to murine heart

Sei Tsunoda, Osam Mazda, Yohei Oda, Yasunori Iida, Satoshi Akabame, Tsunao Kishida, Masaharu Shin-Ya, Hidetsugu Asada, Satoshi Gojo, Jiro Imanishi, Hiroaki Matsubara, Toshikazu Yoshikawa

Journal:

Biochemical and Biophysical Research Communications

Année:

2005

Langue:

english

Fichier:

PDF, 527 KB

english, 2005

Electro-transfer of small interfering RNA ameliorated arthritis in rats

Atsuo Inoue, Kenji A. Takahashi, Osam Mazda, Ryu Terauchi, Yuji Arai, Tsunao Kishida, Masaharu Shin-Ya, Hidetsugu Asada, Toru Morihara, Hitoshi Tonomura, Suzuyo Ohashi, Yoshiteru Kajikawa, Yutaka Kawa

Journal:

Biochemical and Biophysical Research Communications

Année:

2005

Langue:

english

Fichier:

PDF, 351 KB

english, 2005

Comparison of functional non-glycosylated GPCRs expression in Pichia pastoris

Takami Yurugi-Kobayashi, Hidetsugu Asada, Mitsunori Shiroishi, Tatsuro Shimamura, Saeko Funamoto, Naoko Katsuta, Keisuke Ito, Taishi Sugawara, Natsuko Tokuda, Hirokazu Tsujimoto, Takeshi Murata, Norim

Journal:

Biochemical and Biophysical Research Communications

Année:

2009

Langue:

english

Fichier:

PDF, 377 KB

english, 2009

Fluorescence-based optimization of human bitter taste receptor expression in Saccharomyces cerevisiae

Taishi Sugawara, Keisuke Ito, Mitsunori Shiroishi, Natsuko Tokuda, Hidetsugu Asada, Takami Yurugi-Kobayashi, Tatsuro Shimamura, Takumi Misaka, Norimichi Nomura, Takeshi Murata, Keiko Abe, So Iwata, Ta

Journal:

Biochemical and Biophysical Research Communications

Année:

2009

Langue:

english

Fichier:

PDF, 404 KB

english, 2009

Combination vaccine of dendritic cells (DCs) and T cells effectively suppressed preestablished malignant melanoma in mice

Hidetsugu Asada, Tsunao Kishida, Hideyo Hirai, Masaharu Shin-Ya, Jiro Imanishi, Minoru Takeuchi, Osam Mazda

Journal:

Cancer Letters

Année:

2006

Langue:

english

Fichier:

PDF, 480 KB

english, 2006

Soluble TRAIL gene and actinomycin D synergistically suppressed multiple metastasis of TRAIL-resistant colon cancer in the liver

Michiaki Ishii, Masaki Iwai, Yoshinori Harada, Tsunao Kishida, Hidetsugu Asada, Masaharu Shin-Ya, Yoshito Itoh, Jiro Imanishi, Takeshi Okanoue, Osam Mazda

Journal:

Cancer Letters

Année:

2007

Langue:

english

Fichier:

PDF, 272 KB

english, 2007

R039: IL-27-Induced Antitumor Effects against HNSCC in Mice

Masahiro Matsui, Tsunao Kishida, Hidetsugu Asada, Hiroshi Nakano, Shigeru Nakai, Osam Mazda, Yasuo Hisa

Journal:

Otolaryngology - Head and Neck Surgery

Année:

2007

Langue:

english

Fichier:

PDF, 34 KB

english, 2007

Cloning, expression and purification of the anion exchanger 1 homologue from the basidiomycete Phanerochaete chrysosporium

Natsuko Tokuda, Kiyohiko Igarashi, Tatsuro Shimamura, Takami Yurugi-Kobayashi, Mitsunori Shiroishi, Keisuke Ito, Taishi Sugawara, Hidetsugu Asada, Takeshi Murata, Norimichi Nomura, So Iwata, Takuya Ko

Journal:

Protein Expression and Purification

Année:

2011

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2011

Successful genetic transduction in vivo into synovium by means of electroporation

Suzuyo Ohashi, Toshikazu Kubo, Tsunao Kishida, Takumi Ikeda, Kenji Takahashi, Yuji Arai, Ryu Terauchi, Hidetsugu Asada, Jiro Imanishi, Osam Mazda

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 200 KB

english, 2002

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

Haga, Kazuko, Kruse, Andrew C., Asada, Hidetsugu, Yurugi-Kobayashi, Takami, Shiroishi, Mitsunori, Zhang, Cheng, Weis, William I., Okada, Tetsuji, Kobilka, Brian K., Haga, Tatsuya, Kobayashi, Takuya

Journal:

Nature

Année:

2012

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2012

Pleiotrophic functions of Epstein-Barr virus nuclear antigen-1 (EBNA-1) and oriP differentially contribute to the efficiency of transfection/expression of exogenous gene in mammalian cells

Tsunao Kishida, Hidetsugu Asada, Koji Kubo, Yuko T. Sato, Masaharu Shin-Ya, Jiro Imanishi, Kenichi Yoshikawa, Osam Mazda

Journal:

Journal of Biotechnology

Année:

2008

Langue:

english

Fichier:

PDF, 372 KB

english, 2008

Platform for the rapid construction and evaluation of GPCRs for crystallography inSaccharomyces cerevisiae

Shiroishi, Mitsunori, Tsujimoto, Hirokazu, Makyio, Hisayoshi, Asada, Hidetsugu, Yurugi-Kobayashi, Takami, Shimamura, Tatsuro, Murata, Takeshi, Nomura, Norimichi, Haga, Tatsuya, Iwata, So, Kobayashi, T

Journal:

Microbial Cell Factories

Année:

2012

Langue:

english

Fichier:

PDF, 687 KB

english, 2012

[IEEE 2006 IEEE International Symposium on MicroNanoMechanical and Human Science - Nagoya University, Nagoya, Japan (2006.11.5-2006.11.8)] 2006 IEEE International Symposium on MicroNanoMechanical and Human Science - Novel Gene Transduction Procedures in vivo Using the Epstein-Barr Virus-based Artificial Chromosomes

Mazda, Osam, Kishida, Tsunao, Asada, Hidetsugu, Iida, Yasunori, Tsunoda, Sei, Oda, Yohei, Shin-Ya, Masaharu, Yoshikawa, Toshikazu, Matsubara, Hiroaki, Imanishi, Jiro

Année:

2006

Langue:

english

Fichier:

PDF, 7.26 MB

english, 2006

[IEEE 2007 International Symposium on Micro-NanoMechatronics and Human Science - Nagoya, Japan (2007.11.11-2007.11.14)] 2007 International Symposium on Micro-NanoMechatronics and Human Science - Cationic Silica Nanoparticles are Efficiently Transferred into Mammalian Cells

Liu, Li, Takenaka, Toshio, Zinchenko, Anatoly A., Chen, Ning, Inagaki, Shio, Asada, Hidetsugu, Kishida, Tsunao, Mazda, Osam, Murata, Shizuaki, Yoshikawa, Kenichi

Année:

2007

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2007

[IEEE 2008 International Symposium on Micro-NanoMechatronics and Human Science (MHS) - Nagoya, Japan (2008.11.6-2008.11.9)] 2008 International Symposium on Micro-NanoMechatronics and Human Science - Subcellular localization of EBNA1 and oriP that may support the high rate of exogenous gene transfer achieved using the EBV genetic elements

Asada, Hidetsugu, Yoshimura, Shige H., Kishida, Tsunao, Imanishi, Jiro, Mazda, Osam

Année:

2008

Langue:

english

Fichier:

PDF, 4.35 MB

english, 2008

Proteoliposome-based Selection of a Recombinant Antibody Fragment Against the Human M2 Muscarinic Acetylcholine Receptor

Suharni,, Nomura, Yayoi, Arakawa, Takatoshi, Hino, Tomoya, Abe, Hitomi, Nakada-Nakura, Yoshiko, Sato, Yumi, Iwanari, Hiroko, Shiroishi, Mitsunori, Asada, Hidetsugu, Shimamura, Tatsuro, Murata, Takesh

Journal:

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

Année:

2014

Langue:

english

Fichier:

PDF, 526 KB

english, 2014

Effects of cigarette smoke exposure on immune functions in alveolar macrophage

Kobayashi, Kengo, Hirono, Yuriko, Fukuda, Miki, Ishikawa, Hisae, Asada, Hidetsugu, Mazda, Osamu, Nagai, Sonoko, Takeuchi, Toru, Pinkerton, Kent E., Takeuchi, Minoru

Journal:

World Allergy Organization Journal

Année:

2007

Langue:

english

Fichier:

PDF, 128 KB

english, 2007

ESR Studies of N -(Arylthio)- t -butylaminyls

Miura, Yozo, Asada, Hidetsugu, Kinoshita, Masayoshi

Journal:

Bulletin of the Chemical Society of Japan

Année:

1977

Fichier:

PDF, 537 KB

1977

An ESR Study of N -(Alkylthio)arylaminyls. Substituent Effects on ESR Parameters

Miura, Yozo, Asada, Hidetsugu, Kinoshita, Masayoshi

Journal:

Bulletin of the Chemical Society of Japan

Année:

1980

Fichier:

PDF, 888 KB

1980

ELECTRON SPIN RESONANCE SPECTRA OF N -ALKYL- N -(ALKYLTHIO)AMINYLS

Miura, Yozo, Asada, Hidetsugu, Kinoshita, Masayoshi

Journal:

Chemistry Letters

Année:

1978

Langue:

english

Fichier:

PDF, 4.60 MB

english, 1978

Implication of CDK Inhibitors p21 and p27 in the Differentiation of HL-60 Cells

Horie, Nobuyuki, Mori, Tsuyoshi, Asada, Hidetsugu, Ishikawa, Aki, G.Johnston, Patrick, Takeishi, Keiichi

Journal:

Biological & Pharmaceutical Bulletin

Année:

2004

Langue:

english

Fichier:

PDF, 2.65 MB

english, 2004

The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone

Asada, Hidetsugu, Inoue, Asuka, Ngako Kadji, Francois Marie, Hirata, Kunio, Shiimura, Yuki, Im, Dohyun, Shimamura, Tatsuro, Nomura, Norimichi, Iwanari, Hiroko, Hamakubo, Takao, Kusano-Arai, Osamu, His

Journal:

Structure

Année:

2019

Fichier:

PDF, 3.77 MB

2019

The discovery of a new antibody for BRIL-fused GPCR structure determination

Miyagi, Hikaru, Asada, Hidetsugu, Suzuki, Michihiko, Takahashi, Yuichi, Yasunaga, Mai, Suno, Chiyo, Iwata, So, Saito, Jun-ichi

Journal:

Scientific Reports

Année:

2020

Fichier:

PDF, 2.20 MB

2020

Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode

Shiimura, Yuki, Horita, Shoichiro, Hamamoto, Akie, Asada, Hidetsugu, Hirata, Kunio, Tanaka, Misuzu, Mori, Kenji, Uemura, Tomoko, Kobayashi, Takuya, Iwata, So, Kojima, Masayasu

Journal:

Nature Communications

Année:

2020

Fichier:

PDF, 1.22 MB

2020